|
Akademija
medicinskih znanosti Hrvatske
Hrvatski zavod za
javno zdravstvo
Klinika za dječje
bolesti Zagreb
ZNANSTVENI SKUP
Respiratorne virusne infekcije u dječjoj dobi
Pod pokroviteljstvom:
Razreda za medicinske znanosti
Hrvatske akademije znanosti i umjetnosti
Zagreb,
21. rujna 2006.
u 13.30 u Klinici za dječje
bolesti Zagreb, Klaićeva 16.
PROGRAM
13.30-13.40 S. Kolaček: Introduction. Dr. Ogra’s
biographical sketch
13.40-13.55 G. Mlinarić-Galinović i sur.: 11-godišnja
studija RSV-infekcija u Hrvatskoj
13.55-14.25 PL Ogra: RSV. Current understanding of the
disease
14.25-14.40 J. Čepin-Bogović i sur.: Klinička slika I
liječenje RSV-infekcija
14.40-14.55 S. Rabatić i sur.: Immunoreaction to RSV. Our
investigations
14.55-15.10 S. Sternak - Ljubin i sur.: Seroprevalencija
HMPV u Hrvatskoj
15.10-15.40 PL Ogra: Vaccines and development of
autoimmune responses
Dr. Pearay L. Ogra
John Sealy Distinguished Chair Professor and Chairman
(Emeritus), Dept. of Pediatrics at University of Texas Medical
Branch at Galveston, TX and Professor of Pediatrics at
Children's Hospital and State University of New York at Buffalo,
219 Bryant Street Buffalo, NY 14222, USA.
BIOGRAPHICAL SKETCH
Dr. Ogra’s career in academic medicine began in the early
1960’s. His research has focused on natural and experimentally
induced host-pathogen interactions, studies on vaccine efficacy
and vaccine development, and cellular and molecular aspects of
mucosal immunity. His major scientific contributions began in
1968 with the first functional characterization of secretory IgA
and "alimentary" mucosal immunity to poliovirus. In subsequent
series of investigations, he defined the role of secretory IgA
and cellular mucosal immune response to such human infections as
rubella, mumps, hepatitis B and enteroviruses. During the
mid-seventies, his laboratory provided extensive immunologic
characterization of human milk, its role in maternal-neonatal
interactions and childhood infections, and the association of
mammary glands with other mucosal surfaces of the common mucosal
immune system.
Since the early eighties, other investigations from his
laboratory and his other colleagues have identified components
of host-pathogen interactions underlying the pathogenesis of
respiratory and enteric viral infections, notably in
bronchiolitis due to respiratory syncytial virus (RSV) and
gastroenteritis due to rotavirus in man. These include
demonstration, for the first time, of RSV specific IgE antibody
in the respiratory mucosa and its role in viral induced reactive
airway disease. Other innovative experiments from his colleagues
have provided identification of rotavirus specific
receptor-binding sites in villous enterocytes in early infancy,
and the role of bifidobacteria in modulating rotavirus-mucosal
cell interactions. Currently, vaccine development, especially
via the mucosal route is an area of intense scientific effort
throughout the world and the observations from his laboratory on
viral specific secretory IgA have contributed significantly to
the current concepts of secretory immunity and the clinical
exploration of several mucosal vaccines. These investigations
have resulted to date in over 400 original papers and review
articles, and 16 full-length books and monographs, including the
first comprehensive textbook of “Mucosal Immunology”.
In 1991, Dr.
Ogra was appointed the John Sealy Distinguished Chair Professor
and Professor - Chairman, Department of Pediatrics and
Pediatrician-in-Chief, at the Children's Hospital, and Professor
of Microbiology and Immunology at the University of Texas
Medical Branch in Galveston, Texas. He retired from this
position in 2001. During his tenure as the chairman, the
department underwent immense growth in several academic areas.
These included increase in the Federal research funding in the
department by about ten-fold. A new research program funded by
NICHD established one of the first Child Health Research Centers
in the Department of Pediatrics at UTMB and establishment of a
full service Children’s Hospital in Galveston. At the time of
his retirement from the chair, the Department had four endowed
professorships, and an active NIH funded program in child
health.
Dr. Ogra has
continued to remain active in the laboratory as well as the
clinical programs in Infectious Diseases. He returned to State
University of New York and the Children’s Hospital of Buffalo in
early 2000 as Professor of Pediatrics in the division of
Infectious diseases in the department of Pediatrics. During his
investigative career, he has trained over 75 post-doctoral
fellows and PhD students in Microbiology and Immunology. During
his academic career, Dr Ogra has been involved in the training
of over 1000 Pediatric residents both in New York and in Texas.
Dr Ogra has
been elected to membership of the Association of American
Physicians, The Royal Society - Medicine and the American
Society for Clinical Investigation and over 20 other scientific
societies. He received the E. Mead Johnson Award from the
American Academy of Pediatrics and the Stockton Kimball Award
from the State University of New York for outstanding scientific
contributions in pediatrics, and Kalhana Award from Kashmir
cultural and Scientific society. In April 2006, he served as the
Scholar - in - residence at the International vaccine Institute
in Seoul, Korea.
Dr Ogra has
served on several advisory panels at the World Health
Organization, Study Sections of the National Institutes of
Health, Advisory Boards of the Laboratory for Clinical
Investigation - NIAID, National Institute of Environmental
Health Science - NIH, US Armed Forces Research and Development
Command, Maternal and Child Health Research Committee at NICHHD,
and the advisory committees of several international congresses,
FDA Committee on Vaccines and WHO Steering Committee on Measles
and Acute Respiratory Diseases. He has served on the editorial
boards of several scientific journals. He has also served as the
Chairman of the Board, International Pediatric Research
Foundation, Inc., which is responsible for publication of "Pediatric
Research" journal.
Personal Background
Born in
Kashmir, India. Early education in Kashmir. Attained medical
degree in 1961 from the Christian Medical College, Ludhiana, and
Punjab, India. Subsequent medical training in Pediatrics,
Infectious Diseases, Clinical Virology and Immunology at the
upstate Medical center - Binghamton General Hospital, University
of Chicago-Bob's Roberts Children's Hospital (with the late Dr.
Albert Dorfman), New York University-Bellevue Medical Center
(with the Late Dr. Saul Krugman), and at the State University of
New York (with Dr. David Karzon).
|
